*仅供医学专业人士阅读参考众所周知，APOE4是散发阿尔茨海默病（AD）的最强风险基因。大约三年前，首都医科大学宣武医院团队的一项研究显示，亚裔携带APOE4的频率为9%[1]。受影响的人可真不少。去年年底，斯坦福大学团队的一项研究结果表明，APOE ...

当ApoE被传递到转移细胞时，它会中和脂质，当铁死亡开始时脂质会迅速“燃烧”并破坏细胞膜，ApoE会增加细胞的抗氧化能力。综合起来，这些ApoE作用保护黑色素瘤细胞免于溶解，从而降低了体内铁下垂的治疗效果。

A research team led by Prof. Patrizia Agostinis (VIB-KU Leuven) has found that melanoma cell populations protect themselves ...

Researchers from the team of Prof. Patrizia Agostinis (VIB-KU Leuven) have found that melanoma cell populations protect themselves from a form of cell death called ferroptosis by secreting the ...

Revvity's latest solution for specific typing of AD-associated APOE gene is likely to allow assessment of a patient's risk for adverse effects from new anti-amyloid therapy for Alzheimer's.

A recent study suggests that a drug approved for the treatment of seizures may also help treat Alzheimer's in people who do ...

A study suggests that menopausal hormone therapy (MHT) might have moderate effects on brain health, but this depends on past ...

Revvity, Inc. RVTY announced the launch of the in-vitro diagnostic EURORealTime APOE assay in European countries that accept the CE mark on Oct. 2. The assay will likely enable accurate genotyping ...

Lexeo Therapeutics, Inc. (Nasdaq: LXEO), a clinical stage genetic medicine company dedicated to pioneering treatments for genetically defined cardiovascular diseases and APOE4-associated Alzheimer’s ...

Recent research is looking at the way in which cardiovascular issue may play into the development of dementia, with one study suggesting that heparin, a common anticoagulant, may help delay ...

Corder, E.H. et al. HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy. Nature Med. 4, 1182–1184 (1998).