Summary. Doripenem, a member of the β-lactam class of antibiotics, is the newest addition to the carbapenems. It exhibits concentration-independent bactericidal activity against gram-positive ...
These pathogens have reached high rates of resistance to multiple drugs, including last-resort antibiotics called carbapenems. In Italy, a G7 member state, carbapenem-resistance rate was 29% in 2019.
The emergence of resistant to carbapenems Gram-negative bacteria (CR GNB) has severely challenged antimicrobial therapy. Many CR GNB isolates are only susceptible to polymyxins; however ...
Among Gram-negative bacteria – some of the most resistant to antimicrobial drugs – resistance to carbapenems (antibiotics used to treat severe bacterial infections) increased more than any ...
baumannii infections are resistant to carbapenems, with up to 95% of strains resistant in some countries. BioVersys’s lead product, BV100 (rifabutin for infusion), is in clinical development for ...
Drugs called carbapenems are used when an infection cannot be treated with anything else. The spread of resistant Klebsiella pneumoniae was "extremely concerning", researchers from the Sanger ...
They include penicillin and its derivatives, such as methicillin and amoxicillin, as well as other groups of antibiotics known as the cephalosporins, carbapenems, and monobactams. The beta-lactam ring ...