By designing ADCs to bind to specific proteins on the surface of tumour cells, the cytotoxin can be targeted more specifically to cancerous cells, resulting in those cells receiving a longer ...

ADCs can incorporate multiple linkers to increase the concentration of delivered cytotoxin. However, there’s a limit. “Conjugating too many payloads can be counterproductive,” explains Peterson.

Typically, the therapeutic molecule, known as the ADC payload, is a highly potent small-molecule cytotoxin that delivers the therapeutic effect. A linker connects the payload to the mAb ...

Blindfolded and Led to the Woods had been eagerly planning an 18-date tour of the US and Canada, with the first show ...

The FDA has already made more than a dozen cancer drug approval decisions this year and more expected in the next several ...

A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.

Christchurch heavy metal band Blindfolded and Led to the Woods has been denied entry to the United States after being deemed not “big enough” to qualify fo ...

VANCOUVER, British Columbia--(BUSINESS WIRE)--Zymeworks Inc. (NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional biotherapeutics, today announced the publication of ...