By Susha Cheriyedath, M.Sc. Researchers discover a novel protein therapy that recharges exhausted T cells, unleashing their ...

A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that ...

Proteolytic enzymes (proteases) have several potential uses, such as aiding digestion, supporting immunity, improving healing, and more. Your body uses these enzymes to break down protein. While your ...

Loss of Ubp3 resulted in mitochondrial activation, along with a reduction in the glycolytic enzymes - phosphofructokinase 1 (Pfk1) and GAPDH (Tdh2 and Tdh3). This consequently reroutes glucose flux ...

Trypsin enzyme is one of several key enzymes that help digest proteins. People with cystic fibrosis, pancreatitis, or malabsorption may not make enough trypsin enzyme on their own, so they might need ...

Objective We aim to unveil the consequences of mutant Gnas R201C expression on phenotype, transcriptomic profile and genomic dependencies. Data are available in a public, open access repository. Bulk ...

The metabolic requirements of tumor cells are associated with high levels of glutamine consumption to produce energy. The first step is conversion of glutamine to glutamate catalyzed by glutaminase, ...

To determine Adverse Outcomes Evidence (AOE), the hearts of the rats were evaluated through histopathological examination and by measuring myocardial enzyme and cardiac injury markers levels.

This model is based on a critical observation we made: diabetes in animals and patients, and hyperglycemia in cells, all decrease the activity of the key glycolytic enzyme glyceraldehyde-3 ...

NSE is a neuronal isoform of the glycolytic enzyme enolase (2-phospho-d-glycerate hydrolase) that is involved in glucose metabolism. NSE is a dimeric enzyme mainly expressed in neurons (γγ ...