Abstract and Introduction Predicting and Establishing the Clinical Efficacy of a Histamine H Application ... mechanisms of action of H 1-receptor antagonists and to predict their clinical efficacy.

Investigational models like the histamine-induced skin wheal-and-flare ... indicator of the effectiveness of an H 1-receptor antagonist in clinical practice. For the antihistamine desloratadine ...

Read on for more details. Both histamine-2 receptor antagonists (H2 blockers) and proton pump inhibitors (PPIs) decrease ...

investigated the potential of the histamine H1 blocker hydroxyzine to improve sleep in patients with cirrhosis and minimal hepatic encephalopathy. All 35 patients (mean age 56 years [range 36–69 ...