Patients with ankylosing spondylitis and IBD exhibit distinct clinical and radiographic features, compared against those without comorbid IBD.

Background/aims To explore and characterise the clinical phenotype of acute anterior uveitis flares with delayed severity in patients with human leucocyte antigen B27 (HLA-B27)-associated anterior ...

Timely and accurate diagnosis is challenging and relies on identifying a clinical pattern with a combination of clinical, laboratory (HLA-B27 positivity), and imaging findings (eg, structural damage ...

Identified genes include HLA-B27, ERAP1, and IL-23 receptor. Triggers can be exogenous (ie, infection and mechanical stress) or endogenous (ie, gut dysbiosis and loss of epithelial integrity). Immune ...

Features linking this group of diseases include association with HLA-B27, peripheral arthritis that is typically asymmetric and lower limb predominant, and possibly include sacroiliitis ...

Patient age in uveitis diagnoses and treatment plays a significant role, according to research published in American Journal of Ophthalmology.

Idiopathic ankylosing spondylitis is characterised by axial skeletal involvement with ankylosis, but peripheral joint involvement may also occur. It is associated with possession of HLA-B27 in over 90 ...

强直性脊柱炎的病理主要涉及遗传因素、免疫因素、感染因素、内分泌因素以及环境因素等。 1. 遗传因素：强直性脊柱炎具有明显的遗传倾向。相关基因如人类白细胞抗原-B27（HLA-B27）与本病的发病密切相关。如果家族中有强直性脊柱炎患者，其亲属患病的风险会增加。 2.

001). HLA-B27 positivity was less likely in women, appearing among 65.8% of women vs. 78.9% of men (P < .001). However, women also reported healthier behaviors than men, with lower proportions of ...

腰痛的成因可以追溯到正常解剖结构的损伤，比如椎体骨折和腰肌劳损，也可能是全身性疾病的炎症引发的结果，如类风湿关节炎和脊柱炎。此外，直接感染、肿瘤的形成、代谢性疾病，甚至某些脏器的问题都可能导致腰部疼痛。例如，孕期由于脊柱负担加重也会造成腰痛。

Fibromyalgia and rheumatoid arthritis can cause similar symptoms like pain, reduced mobility in muscles, and exhaustion. The symptoms may be difficult to distinguish if a person has both conditions.

In PsA the main additional associations have been found to be with HLA-B27, chiefly in patients with predominant spinal disease, HLA-B38 and HLA-B39, and the class II antigen HLA-DR4. These findings ...