Patient age in uveitis diagnoses and treatment plays a significant role, according to research published in American Journal of Ophthalmology.
Patients with ankylosing spondylitis and IBD exhibit distinct clinical and radiographic features, compared against those without comorbid IBD.
腰痛的成因可以追溯到正常解剖结构的损伤,比如椎体骨折和腰肌劳损,也可能是全身性疾病的炎症引发的结果,如类风湿关节炎和脊柱炎。此外,直接感染、肿瘤的形成、代谢性疾病,甚至某些脏器的问题都可能导致腰部疼痛。例如,孕期由于脊柱负担加重也会造成腰痛。
强直性脊柱炎的病理主要涉及遗传因素、免疫因素、感染因素、内分泌因素以及环境因素等。 1. 遗传因素:强直性脊柱炎具有明显的遗传倾向。相关基因如人类白细胞抗原-B27(HLA-B27)与本病的发病密切相关。如果家族中有强直性脊柱炎患者,其亲属患病的风险会增加。 2.
Fibromyalgia and rheumatoid arthritis can cause similar symptoms like pain, reduced mobility in muscles, and exhaustion. The symptoms may be difficult to distinguish if a person has both conditions.
001). HLA-B27 positivity was less likely in women, appearing among 65.8% of women vs. 78.9% of men (P < .001). However, women also reported healthier behaviors than men, with lower proportions of ...
根据以上典型症状,医生为他完善了相关检查,结果提示人白细胞抗原B27(HLA-B27)阳性,骶髂关节核磁共振可见骶髂关节面骨髓水肿,最终诊断为 ...
根据以上典型症状,医生为他完善了相关检查,结果提示人白细胞抗原B27(HLA-B27)阳性,骶髂关节核磁共振可见骶髂关节面骨髓水肿,最终诊断为强直性脊柱炎。张先生惊讶不已,没想到反反复复的眼疾居然是因强直性脊柱炎引起的。 医生解释,强直性脊柱炎 ...
Timely and accurate diagnosis is challenging and relies on identifying a clinical pattern with a combination of clinical, laboratory (HLA-B27 positivity), and imaging findings (eg, structural damage ...
Identified genes include HLA-B27, ERAP1, and IL-23 receptor. Triggers can be exogenous (ie, infection and mechanical stress) or endogenous (ie, gut dysbiosis and loss of epithelial integrity). Immune ...
Results: This study identified HLA class I–binding variant peptides derived from canonical proteins, which had single amino-acid substitutions not attributed to genetic mutations or RNA editing. These ...