Armed robbery in Revesby14 天
FOXM1, PD-L1 Linked to CDK4/6-MEK Resistance in Nerve Tumors
As highlighted in the abstract of this paper, malignant peripheral nerve sheath tumors (MPNSTs) are aggressive, Ras-driven sarcomas characterized by the loss of the NF1 tumor suppressor gene and the ...
headtopics15 天
The role of FOXM1 and PD-L1 in malignant peripheral nerve sheath tumor resistance
Currently, MPNSTs lack effective therapies. Recently, the authors demonstrated the remarkable efficacy of dual CDK4/6-MEK inhibition in mice with de novo MPNSTs, which was further enhanced by ...
News Medical on MSN15 天
The role of FOXM1 and PD-L1 in malignant peripheral nerve sheath tumor resistance
Currently, MPNSTs lack effective therapies. Recently, the authors demonstrated the remarkable efficacy of dual CDK4/6-MEK ...
EurekAlert!15 天
FOXM1 and PD-L1 in CDK4/6-MEK resistance in nerve tumors
Currently, MPNSTs lack effective therapies. Recently, the authors demonstrated the remarkable efficacy of dual CDK4/6-MEK inhibition in mice with de novo MPNSTs, which was further enhanced by ...