We demonstrate that these CDK4/6i-induced lysosomal alterations render breast cancer cells sensitive to lysosomotropic agents, such as L-leucyl-L-leucine methyl ester (LLOMe) and salinomycin.

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Clinical Laboratory of China-Japan Union Hospital, Jilin University, Changchun, China The liver performs crucial roles in energy metabolism, detoxification, and immune regulation. Hepatic diseases, ...

Ferroptosis induces significant changes in mitochondrial morphology, including membrane condensation, volume reduction, cristae alteration, and outer membrane rupture, affecting mitochondrial function ...

Request To Download Free Sample of This Strategic Report @ Feed antibiotics are used extensively in animal husbandry to prevent disease, promote growth, and improve feed efficiency. With the rising ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. In this work, nanometric niosomes (158 ± 38 nm) presenting a narrow size distribution ...