To alleviate the limitations discussed above, we developed a novel PCR-based application – coamplification at lower denaturation temperature (COLD)-PCR, [24] that preferentially enriches ...

We have recently developed coamplification at lower denaturation temperature-PCR (COLD-PCR) to resolve this limitation. This novel form of PCR selectively amplifies low-abundance DNA variants from ...

Department of Oncology and Radiotherapy, Youjiang Medical College for Nationalities Affiliated Hospital, Baise, China. Lung cancer is one of the malignant tumor diseases with high morbidity and high ...

This study provides important new insights into the contributions of local DNA features to the complex molecular mechanisms and dynamics of copy number variation (CNV) formation during adaptive ...