recent reports have now revealed roles for human 2-oxoglutarate–dependent oxygenases in histone and nucleic acid demethylation and in signaling protein hydroxylation. The emerging role of these ...

This result suggested that the demethylation that led to yellowness and obesity occurred in early development. Despite this suggestion, not all the mice pups that Jirtle observed grew to be unhealthy.

They found that ischemic injury induces astrocytes to modify their methylome to a stem cell state, involving the methylation ...

What is Known About the Estrogen Deficiency of Menopause & Specific Autoimmune Diseases It is known that many natural, pathological and therapeutic conditions can change serum estrogen levels ...

KEY POINTS A 65-year-old woman presented to the emergency department with an 8-day history of progressive leg weakness and ...

Diverse frequencies among individuals from various racial and ethnic backgrounds can result in modified therapeutic strategies. Whereas the CYP2D6*4 allele is present at a high frequency in ...