Glutamate uptake via EAATs serves as a major mechanism for regulating the extracellular concentration of glutamate and preventing glutamate excitotoxicity. Glutamate uptake is mainly accomplished by ...
Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...
Brain injury resulting from hypoxia (oxygen deprivation) or ischemia (restricted blood flow) represents a major challenge in medical research and clinical ...
How our cells dispose of waste and ways to control it Date: January 7, 2025 Source: University of Freiburg Summary: Cells degrade components that are no longer needed through autophagy. New ...
Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder Researchers studying brain cells from Huntington's patients show that the ...
Diabetic patients frequently suffer from retinopathy, nephropathy, neuropathy and accelerated atherosclerosis. The loss of endothelial function precedes these vascular alterations. Here we report ...
Trial Nutrients. 2016;8(1):53-. doi:10.3390/nu8010053 Dong, Xx., Wang, Y. & Qin, Zh. Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases. Acta ...