Taking a pill is the easiest, least invasive way to take medicine, but unfortunately, not all drugs work that way. Now, ...

For many people with cancer, intravenous (IV) infusions of chemotherapy are their best chance at a cure. But these infusions ...

A small molecular tag added to a drug molecule can make drugs normally administered through an IV effective as oral pills.

The FDA approved Zelboraf (vemurafenib) for the rare blood cancer, Erdheim-Chester disease with BRAF V600 mutation, adding to an existing use in late-stage melanoma. This is the first drug ...

For many people with cancer, IV infusions of chemotherapy are their best chance at a cure. But these infusions can be ...

Adults with a type of skin cancer called melanoma. Tecentriq Hybreza may be used with the medicines cobimetinib and vemurafenib in patients with melanoma when their skin cancer: has spread to ...

The VE-Basket trial [NCT01524978] is a phase II basket trial evaluating early signals of vemurafenib activity in patients with non-melanoma cancers harbouring BRAF V600 mutations. The initial ...

PTC 是最常见的甲状腺癌，需要使用威罗菲尼(vemurafenib)进行药物治疗。但是， 哈佛医学院的一个团队在研究中有了一个新发现：FDA批准的用于治疗 ...

They include RAF inhibitors, such as sorafenib and vemurafenib, or MEK inhibitors such as selumetinib (AZD6244). Since trials investigating the potential use of anti-BRAF agents in the management ...

Melanoma is a type of cancer that originates from melanocytes, the cells responsible for producing skin pigment, and is known ...

Nat. Cell. Biol. 20: 104-115. Akihiro Yoshida, Eric K. Lee, and J. Alan Diehl (2016). Induction of Therapeutic Senescence in Vemurafenib-Resistant Melanoma by Extended Inhibition of CDK4/6. Cancer Res ...

We have summarized in this article the current state of combination therapy of approved targeted drugs and irradiation. Since the introduction of the first targeted compounds almost (trastuzumab ...